Assessment of Clinical Response
According to statistics back in 2012 there were approximately 981 drugs in development for cancer and this statistic is probably higher now. Some of the main challenges are how to…
Continue readingPharmacokinetics and Pharmacodynamics of Anticancer Drugs
In order to identify the correct dose of any therapeutic agent there are 2 pharmacological phases: Pharmacokinetic phase in which the dose, dosage form, frequency, and route of administration are…
Continue readingHow Do We Know if Drugs Are Carcinogenic?
We often see in the news headlines information of some drug being potentially carcinogenic or contaminated with substance that is potentially carcinogenic. But what that means and how do we…
Continue readingIs It Possible to Have an Anti – Cancer Therapeutic Vaccine?
There are many observations in melanoma lesions where the immune system is able to act against the tumours and usually this is a sign of a good prognosis. However, over…
Continue readingThe Role of MicroRNAs in Human Diseases
It is very common that microRNAs are overexpressed or inactivated in human diseases. The best approach in such cases is to either target the overexpressed microRNA to inactivate it or…
Continue readingCould Response – Based Dose Be the Future of Patient Care?
FDA report showed that most drugs are effective in only 25-62% of the patients. That probably make you wonder why they are approved and prescribed to patients? The answer to…
Continue readingAdopting Orphan Drugs in Different Therapeutic Areas
What happens if a newly developed drug fails in the tested indication? Very often such drugs are abandoned if the developers think they will not be able to be used…
Continue readingCan We Predict Adverse Reactions?
One of the big challenges in drug development is our limited ability to identify potential adverse reactions associated with new therapeutics. Pharmacogenomics provides a great opportunity in understanding the mechanisms…
Continue readingCan AL Help Speed Up Drug Development?
Artificial intelligence and machine-learning are novel exciting tools which we hope will help drug development. AI is analysis of very large data sets with statistical machine-learning methods. The simple way…
Continue reading3D Printing and Its Potential Application in Drug Development
Three-dimensional printing (3D printing) is gaining popularity in different areas from manufacturing to medicine. It is believed to be considered the beginning of the new industrial revolution. Not surprising 3D printing…
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