In order to identify the correct dose of any therapeutic agent there are 2 pharmacological phases: Pharmacokinetic phase in which the dose, dosage form, frequency, and route of administration are…
Continue readingWe often see in the news headlines information of some drug being potentially carcinogenic or contaminated with substance that is potentially carcinogenic. But what that means and how do we…
Continue readingThere are many observations in melanoma lesions where the immune system is able to act against the tumours and usually this is a sign of a good prognosis. However, over…
Continue readingIt is very common that microRNAs are overexpressed or inactivated in human diseases. The best approach in such cases is to either target the overexpressed microRNA to inactivate it or…
Continue readingFDA report showed that most drugs are effective in only 25-62% of the patients. That probably make you wonder why they are approved and prescribed to patients? The answer to…
Continue readingWhat happens if a newly developed drug fails in the tested indication? Very often such drugs are abandoned if the developers think they will not be able to be used…
Continue readingOne of the big challenges in drug development is our limited ability to identify potential adverse reactions associated with new therapeutics. Pharmacogenomics provides a great opportunity in understanding the mechanisms…
Continue readingArtificial intelligence and machine-learning are novel exciting tools which we hope will help drug development. AI is analysis of very large data sets with statistical machine-learning methods. The simple way…
Continue readingThree-dimensional printing (3D printing) is gaining popularity in different areas from manufacturing to medicine. It is believed to be considered the beginning of the new industrial revolution. Not surprising 3D printing…
Continue readingIt is not a secret that the research and development in the pharmaceutical industry is very costly, time-consuming, risky and not particularly efficient. According to estimates bringing new drugs on…
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