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CircRNA as cancer biomarker and potential therapeutic target
Circular RNAs (circRNAs) are class of long, non-coding RNAs, which are very tissue specific. Initially these circRNAs were thought to have no biological function. In the recent research there are more and more evidence that these types of RNA are present in mammalian...
Cancer Immunotherapy and Killer Cells
Cancer immunotherapy is a promising field in drug development because it provides new treatment options for various cancers, especially in combination with standard of care. Immune system can recognize and eliminate tumour cells and is responsible for targeting most...
Can you measure bone lesions with RECIST 1.1
This is a short overview of how to use Anderson criteria as modification to RECIST 1.1 to measure bone lesions. The criteria was developed by The University of Texas MD Anderson Cancer Center back in 2004 and is gaining popularity in clinical research because it...
Practical Clinical Trials, Issue 4 2017
We are happy to release out annual edition of Practical Clinical Trials magazine for 2017. It features materials which were published on our web site in 2017. It includes some very exciting reviews on latest trends in oncology therapy and diagnostics and lots of...
MicroRNAs and cancer
MicroRNAs (miRNAs) are non-coding RNAs, which are used generally to down-regulate gene expression from messenger RNA (mRNA) by binding to it. miRNAs are getting popular in potential application in cancer therapy. They could be used either to replace tumour suppressive...
Clinical research and brain metastases: the unique challenges
According to estimates in US approximately 6 – 14% of newly diagnosed patients will develop brain metastases. Almost 45% of patients with lung cancer will develop brain metastases, based on statistical data. Unfortunately there is a poor prognosis for patients with...
CRISPR – Cas9: glimpse into the future of gene editing and oncology therapy
Gene editing techniques are exciting for scientist and oncologists who hope that they will give a new approach in treating cancer and even opportunity to eradicate it all. The idea of gene editing has been around for some time, however so far there was no technique... Practical Clinical Trials, Issue 4 2017
We are happy to release out annual edition of Practical Clinical Trials magazine for 2017. It features materials which were published on our web site in 2017. It includes some very exciting reviews on latest trends in oncology therapy and diagnostics and lots of...
Practical Clinical Trials Magazine, issue 3 2016
This is the third edition of our free magazine Practical Clinical Trials, which represents articles published in 2016. You can download the magazine here: DOWNLOAD 0 likesPlease follow and like...
White paper: Clinical trials – Recruitment strategies
This white paper is dedicated to one of the clinical research communities’ hot topics – recruitment. We will discuss different recruitment strategies and their advantages and disadvantages from practical point of view and also we hope to give some new ideas for...
Free magazine: Practical Clinical Trials, issue 2 2015
We are happy to present the second edition of our free annual magazine “Practical Clinical Trials”, which contains reviews and analysis on clinical trials set up, SAE reporting, regulatory requirements, etc. Download here 0 likesPlease follow...