Is It Possible to Have an Anti – Cancer Therapeutic Vaccine?
There are many observations in melanoma lesions where the immune system is able to act against the tumours and usually this is a sign of a good prognosis. However, over…
Continue readingClinical Research Review
The Role of MicroRNAs in Human Diseases
It is very common that microRNAs are overexpressed or inactivated in human diseases. The best approach in such cases is to either target the overexpressed microRNA to inactivate it or…
Continue readingCould Response – Based Dose Be the Future of Patient Care?
FDA report showed that most drugs are effective in only 25-62% of the patients. That probably make you wonder why they are approved and prescribed to patients? The answer to…
Continue readingAdopting Orphan Drugs in Different Therapeutic Areas
What happens if a newly developed drug fails in the tested indication? Very often such drugs are abandoned if the developers think they will not be able to be used…
Continue readingCan We Predict Adverse Reactions?
One of the big challenges in drug development is our limited ability to identify potential adverse reactions associated with new therapeutics. Pharmacogenomics provides a great opportunity in understanding the mechanisms…
Continue readingCan AL Help Speed Up Drug Development?
Artificial intelligence and machine-learning are novel exciting tools which we hope will help drug development. AI is analysis of very large data sets with statistical machine-learning methods. The simple way…
Continue reading3D Printing and Its Potential Application in Drug Development
Three-dimensional printing (3D printing) is gaining popularity in different areas from manufacturing to medicine. It is believed to be considered the beginning of the new industrial revolution. Not surprising 3D printing…
Continue readingWhy New Drugs Fail?
According to current data average time and cost of a new drug to reach the market is 12 years and costs £1.15 billion but what is not included in this…
Continue readingInnovative Clinical Trial Designs: Overview
Those who have worked on clinical trials for many years probably remember the rigidity of the clinical protocols and how often clinicians complained that the study design is out of…
Continue readingIs Clinical Trial Design Fit for Purpose?
It is not a secret that the research and development in the pharmaceutical industry is very costly, time-consuming, risky and not particularly efficient. According to estimates bringing new drugs on…
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